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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

If you are taking any other type of nitrate or alpha-blocker, including anothyronine based product, talk to your doctor before using Cialis. Your doctor will monitor you carefully for any side effects and ensure that you are taking met±2.5% nitrates or nitrite medications. If you are taking any other nitrate or alpha-blocker, talk to your doctor before using Cialis.

C.

Cialis (tadalafil) can interact with certain foods and beverages, so it is contraindicated to use this medication with a type of foods or supplements containing nitrates or alpha-blockers. While this interaction is usually less severe than nitrates or alpha-blockers, it can still be a serious side effect if used with a diet that includes grapefruit and grapefruit juice. If you are using a diet that includes alcohol with tadalafil, avoid while using this medication.

D.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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Tell them about any and all medications, prescription drugs, and supplements you are taking before starting Cialis.

As with all prescription medications, inform your doctor of any medical conditions management will be required.

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Generic Cialis – Generic Cialis

Cialis is a popular medication for treating erectile dysfunction (ED) in men. Generic Cialis is a brand name, not a prescription medication. It is available in both brand name and generic forms.

Cialis comes in various strengths, including:

  1. 25 mg
  2. 50 mg
  3. 100 mg

Cialis can vary in price. While most men will find a 50 mg tabletixir at a pharmacy, some men find a lower price at larger pharmacies.

Generally, the brand name Cialis can be purchased at a significantly lower price than its generic counterpart. As a result, some men find Cialis to be a more affordable option.

Cialis can be taken with or without food. However, some men find a 10 mg dose sufficient for them. Some men find a 10 mg dose more effective.

Cialis pricing

The average retail price of Cialis is $15.08. However, the average cost for a 20 mg tabletixir at a pharmacy is $8.83. As a result, some men find a 20 mg dose more affordable than their lower cost generic counterpart.

Some men find a 20 mg dose more effective than a 10 mg dose. However, some men find a 10 mg dose more affordable than a 20 mg dose.

Most men find Cialis to be a effective treatment for ED.

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The drug information provided here is only a summary and does not contain all the list of possible side effects and drug interactions regarding this medication. Be sure to contact your doctor or pharmacist if you have any specific question or concern. If you require any advice or information about the drugs on this page, a medical condition or treatment advice, you should always speak to a healthcare professional.

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Prescriptions dispensed from Canada are dispensed by: Candrug Pharmacy, ID#18985 604-543-8711. Pharmacy Manager: Carol Hou. Pharmacy Address: Unit #202A, 8322-130th Street, Surrey, British Columbia, Canada V3W 8J9. This pharmacy is duly licensed in the province of British Columbia, Canada by the College of Pharmacists of BC.

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